Prokaryotic Cell Structure: The Nucleoid

Learning Objectives for "Prokaryotic Cell Structure: The Nucleoid"

After completing this section you should be able to perform the following objectives.

1. Define genome.

2. Describe the composition of the bacterial nucleoid.

3. State the function of histone-like proteins in bacterial DNA.

4. Name the enzymes that enables bacterial DNA to become circular, supercoiled, and unwind during DNA replication.

5. State the function of DNA.

6. Briefly state how the following antibacterial chemotherapeutic agents affect bacteria:

a. fluoroquinolones (norfloxacin, lomefloxacin, fleroxacin, ciprofloxacin, enoxacin, trovafloxacin, etc.)

b. trimethoprim and sulfamethoxazole