BIOL 230 Lectures: Unit 5 Table of Contents BIOL 230 Lectures: Table of Contents BIOL 230 Lab Manual: Table of Contents Doc Kaiser's Microbiology Web Site BIOL 230 WWW Web Page Biology Tutorials

BIOL 230 MICROBIOLOGY LECTURE E-TEXT UNIT 5

MICROBIOLOGY LEARNING OBJECTS

UNIT 5

ADAPTIVE IMMUNITY

 

I. INTRODUCTION

A. Overview of Adaptive Immunity

B. Major Cells and Key Cell Surface Molecules Involved in the Immune Responses

1. MHC Molecules

2. Antigen-Presenting Cells (APCs)

3. B-Lymphocytes (B-Cells)

4. T4-Lymphocytes (T4-Cells)

5. Th1,Th2, and Th17 Cells

6. Regulatory T-Lymphocytes (T-reg Cells)

7. T8-Lymphocytes (T8-Cells)

8. Natural Killer T- Lymphocytes (NK cells)

9. Natural Killer Cells (NK Cells)

C. The Lymphoid System

D. An Overview of the Steps Involved in Adaptive Immune Responses

II. HUMORAL IMMUNITY

A. Antibodies (Immunoglobulins)

1. An Overview

2. Antibody Structure

3. The 5 Classes (Isotypes) of Human Antibodies

4. Generation of Antibody Diversity

5. Clonal Selection and Clonal Expansion

6. The Steps Involved in Antibody Production

7. Anamnestic (Memory) Response

B. Ways That Antibodies Help to Defend the Body

1. An Overview

2. Opsonization

3. Cytolysis by the Membrane Attack Complex (MAC)

4. Antibody-dependent Cellular Cytotoxicity (ADCC) by NK Cells

5. Neutralization of Exotoxins

6. Neutralization of Viruses

7. Preventing Bacterial Adherence

8. Agglutination of Microorganisms

9. Immobilization of Bacteria and Protozoans

C. Naturally and Artificially Acquired Active and Passive Immunity

1. Naturally Acquired Immunity

2. Artificially Acquired Immunity

D. Monoclonal Antibodies

III. CELL-MEDIATED IMMUNITY

A. Cell-Mediated Immunity: An Overview

B. The Steps Involved in Cell-Mediated Immunity

C. Ways That Cell-Mediated Immunity Help to Defend the Body

1. Activating Antigen-Specific Cytotoxic T- Lymphocytes (CTLs)

2. Activating Macrophages and NK Cells

3. Stimulating Cells to Secrete Cytokines

D. Active and Passive Immunotherapy to Stimulate Cell-Mediated Immunity against Tumors

IV. IMMUNODEFICIENCY

A. An Overview

B. Primary Immunodeficiency

C. Secondary Immunodeficiency

V. HYPERSENSITIVITIES

A. An Overview

B. Immediate Hypersensitivities

1. Type I

2. Type II

3. Type III

4. Type V

C. Delayed Hypersensitivities (Type IV)

D. Superantigens

BIOL 230 Lectures: Unit 5 Table of Contents BIOL 230 Lectures: Table of Contents BIOL 230 Lab Manual: Table of Contents Doc Kaiser's Microbiology Web Site BIOL 230 WWW Web Page Biology Tutorials