Objectives Chapter 18 Derivatives of Carboxylic Acids Brown, Foote & Iverson

Read Chapter 18 Study Key reactions 1-15,17,18,19, (Pg. 714-717)

  1. Be able to give the IUPAC name of any acid chloride, anhydride, amide, ester, nitrile lactone, or lactam having up to twelve carbon atoms in its structure or if given the name of any compound containing the functional groups mentioned above, be able to draw its structure.
  2. Given the ir spectrum of a compound be able to determine if a carbonyl group is present without the aide of a book.
  3. Be able to give the products which would result when a given acid chloride is reacted with a) water, b) an alcohol, c) ammonia, d) a primary amine, e) a secondary amine or f) an aromatic (in the presence of aluminum chloride).
  4. Be able to give the structure products which would result when a given ester or given amide is reduced with excess lithium aluminum hydride followed by hydrolysis.
  5. Be able to give the structure of the products which would result when a given ester is reacted with a) water in the presence of acid, b) hydroxide ion in basic solution) an alcohol in the presence of acid catalyst, (transesterification), d) ammonia e) a primary amine.
  6. Be able to give the products which would result when an acid anhydride is reacted with a) water, b) an alcohol, c) ammonia, an aromatic in the presence of aluminum chloride.
  7. Be able to show the structure of the product which would result when a given ester is reacted with two mole equivalents of a Grignard reagent (RMgBr)
  8. Be able to give the structure of the products which would result when a given amide were heated under reflux with a) water under acid conditions (hydrolysis), b) hydroxide ion in aqueous solution (basic hydrolysis).
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  9. Be able to show the product, which would result when a nitrile is reduced with lithium aluminum hydride followed by hydrolysis.
  10. Be able to work correctly the problems in chapter 18 18.1(pg 685) 18.2 18.4 (pg 699) 18.6 (pg 703), 18.7 (pg 705) 18.8 (pg 708)18.10 and 18.11((pg 713) At the end of chapter 18try these problems: 12, 13, 14, 15, 16, 17, 19, 20. 22, 23, 24, 25, 26, 27, 35:

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